A SIMULATION-OPTIMIZATION APPROACH TO DETERMINE OPTIMUM FEATURES OF DETENTION ROCKFILL DAMS UNDER FLOOD CONDITION

A simulation-optimization approach to determine optimum features of detention rockfill dams under flood condition

Detention rockfill dams are one of the structural methods that can control flood risks with no impermeable core or membrane.These dams decrease the maximum discharge of flood hydrograph and postpone the time of its occurrence reducing life and financial losses in downstream.In this research study, maybe for the first flexcon reverse osmosis water s

read more

Structural modelling of the lumenal domain of human GPAA1, the metallo-peptide synthetase subunit of the transamidase complex, reveals zinc-binding mode and two flaps surrounding the active site

Abstract Background The transamidase complex is a molecular machine in the endoplasmic reticulum of eukaryotes that attaches a glycosylphosphatidylinositol (GPI) lipid anchor to substrate proteins after cleaving a C-terminal propeptide with a defined sequence signal.Its five subunits are very hydrophobic; thus, solubility, heterologous expression a

read more